Related Sites

Johns Hopkins Department of Neurology

Kennedy Krieger Institute

Kirby Center for Functional Brain Imaging

Johns Hopkins  University School of Medicine

Johns Hopkins University

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The Johns Hopkins Department of Neurology

NIMLAB Members

John E. Desmond, Ph.D.
Director of Neuroimaging and Modulation Lab (NIMLAB),
Professor, Department of Neurology

Johns Hopkins University


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Phone: (410) 502-3583



Ph.D., Psychology
University of Massachusetts, Amherst


M.S., Psychology
University of Massachusetts, Amherst


B.A., Psychology, Summa Cum Laude
University of South Florida, Tampa

Research Interests

My research focuses broadly on neuroimaging and, more recently, transcranial magnetic stimulation methods to investigate neural correlates of behavior. Some specific areas of interest are: The contributions of the cerebellum, and cerebro-cerebellar circuits, to cognition. The effects of long-term alcohol consumption on cognition, functional brain activation, brain structure, and brain connectivity. Aging effects on awareness and cerebro-cerebellar function.  Integration of transcranial magnetic stimulation with functional MRI to assess brain connectivity.

Representative Publications

Brewer, J. B., Zhao, Z., Desmond, J. E., Glover, G. H., & Gabrieli, J. D. E. (1998). Making memories: Brain activity that predicts how well visual experience will be remembered. Science, 281, 1185-1187.


Desmond, J. E., & Fiez, J. A. (1998). Neuroimaging studies of the cerebellum: Language, learning and memory. Trends in Cognitive Sciences, 2, 355-362.


Desmond, J. E., Gabrieli, J. D. E., & Glover, G. H. (1998). Dissociation of frontal and cerebellar activity in a cognitive task: Evidence for a distinction between selection and search. Neuroimage, 7, 368-376.


Desmond, J. E. & Chen S. H. A. (2002). Ethical issues in the clinical application of fMRI: Factors affecting the validity and interpretation of activations. Brain and Cognition, 50, 482-497.


Desmond, J. E., & Glover, G. H. (2002). Estimating sample size in functional MRI (fMRI) neuroimaging studies: Statistical power analyses.  Journal of Neuroscience Methods, 118, 115-128.


Desmond, J. E., Chen, S. H., DeRosa, E., Pryor, M. R., Pfefferbaum, A., & Sullivan, E. V. (2003). Increased frontocerebellar activation in alcoholics during verbal working memory: an fMRI study. Neuroimage, 19, 1510-1520.


Chen, S. H. A. & Desmond, J. E. (2005) Cerebro-cerebellar networks during articulatory rehearsal and verbal working memory tasks. Neuroimage, 24, 332-338.


Chen, S. H. A., & Desmond, J. E. (2005). Temporal dynamics of cerebro-cerebellar network recruitment during a cognitive task. Neuropsychologia, 43, 1227-1237.


Kirschen M. P., Chen, S. H. A., Schraedley-Desmond P., & Desmond J. E. (2005). Load and practice dependent increases in cerebro-cerebellar activation in verbal working memory: An fMRI study. Neuroimage, 24, 462-472.


Desmond, J. E., Chen, S. H. A., & Shieh PB. (2005). Cerebellar transcranial magnetic stimulation impairs verbal working memory.  Annals of Neurology, 58, 553-560.


Kirschen, M.P., Davis-Ratner, M.S., Jerde, T.E., Schraedley-Desmond, P. and Desmond, J.E., Enhancement of phonological memory following Transcranial Magnetic Stimulation (TMS) (2006), Behavioural Neurology, 17, 187-194.


Cheng, DT, Disterhoft, JF, Power, JM, Ellis, DA, Desmond, JE. Neural substrates underlying human delay and trace eyeblink conditioning (2008) Proceedings of the National Academy of Sciences U S A, 105, 8108-13.


Marvel, CL and Desmond, JE. The contributions of cerebro-cerebellar circuitry to executive verbal working memory (2010) Cortex, 46, 880-895.

Yau, J.M., Hua, J., Liao, D.A. and Desmond, J.E. Efficient and robust identification of cortical targets in concurrent TMS-fMRI experiments (2013) Neuroimage, 76, 134-144.

Keren-Happuch, E., Chen, S.H.A., Ho, M-H.R., and Desmond, J.E. A meta-analysis of cerebellar contributions to higher cognition from PET and fMRI Studies (2014) Human Brain Mapping, 35, 593-615.

Yau, J.M., Celnik, P., Hsiao, S.S., and Desmond, J.E. Feeling better: separate pathways for targeted enhancement of spatial and temporal touch (2014), Psychological Science, 25, 555-565.